Analgesics, translated literally from ancient Greek translated as “without pain”, also referred to as painkillers. Analgesic medicine are natural, semisynthetic and synthetic origin and intended for analgesic effect. Can weaken or completely eliminate the pain.
Analgesics WHO classification
Analgesics for pain may have anti-inflammatory and antipyretic effect. The world health organization classifies all painkillers to anti-inflammatory and opioid analgesics.
Opioid analgesics, in turn, are divided further into 2 subtypes:
• Agonists of opioid receptors – morphine and oxycodone
• Agonist-antagonists and partial agonists of opioid receptors
What does the opioid analgesic mean
Opioid analgesics are used during short-term intense pain. Sold only by prescription. Long-term intake of narcotic analgesics cause addiction and withdrawal symptoms.
Opioid analgesics affect the brain and spinal cord. It can be prescribed by a doctor when you can’t receive NSAIDs due to allergies, impaired renal function and liver, diseases of the gastrointestinal tract. Not assigned to the patient if his story was the abuse of drugs, alcohol. To determine suitability for long-term use of opioid analgesics, the doctor uses a tool such as DIRE (Diagnosis, Intractability, Risk and Efficacy). A high score means that the patient can be treated with opioids.
Opioid analgesic pain medicine in the abrupt cancellation may cause symptoms such as nausea, nervousness, frequent mood changes, insomnia, headache, sweating.
Anti-inflammatory analgesics
Anti-inflammatory analgesics are divided into the following varieties:
• Salicylic acid derivatives
• Derivatives phenacetin
• Pyrazolone derivatives
Salicylic acid derivatives (e.g. aspirin) used for mild pain. The drug also has anti-inflammatory effect. Derivatives phenacetin aspirinate can include analgesics, nonsteroidal anti-inflammatory drugs. To such belongs drugs ibuprofen, naproxen, fenoprofen. Pyrazolone derivatives in many countries are not applied due to risk of agranulocytosis.
When choosing analgesic medicine should consider the following factors: the origin of pain, interactions with other drugs you take, the intensity of the pain, allergic reactions, chronic disease. The right decision is always to consult your doctor.
What is topical analgesic
Topical analgesic pain medicine acts directly on the location of the pain, for example when you stretch the muscles from the pain or trauma. The advantage of local painkillers that the number and severity of the side effects are minimal. These medicines come in the form of a gel, cream or spray.
Topical analgesic can include components such as:
• Menthol, oil of evergreens and camphor, which have anti-inflammatory action. These components can create both a cooling and warming effect.
• Salicylates will help with pain in the joints, especially those that are located close to the skin: elbow, knee, knuckles.
• Capsaicin is the main component of chili peppers. It has a powerful warming effect. Burning and tingling you need to endure, over time this feeling fades and finally disappears. Creams and gels based on capsaicin good help for pain in the joints and nerves diabetic.
What does do analgesic
Analgesics for pain unlike anesthetics do not block the conduction of nerve impulses, does not affect the mind or alter sensory perception.
WHO analgesic ladder
The analgesic ladder was developed by the World Health Organization with the aim to offer appropriate and effective treatment to patients with cancer and other diseases with intense pain. According to the table therapy using analgesics was as follows:
1. The appointment of opioid analgesics.
2. If therapy is ineffective, administration of a weak opioid in addition to the non-opioid analgesic.
3. In case of treatment failure, the appointment of a strong opioid and non-opioid analgesic.
The analgesic ladder has been adapted and today there are 4 stages of pain intensity and pain therapy.
1. Non-opioid analgesic, non-steroidal anti-inflammatory drug.
2. Weak opioid
3. Strong opioids (methadone) by oral route of administration, transdermal patches
4. Receptor blockers, microinfusion pump, epidural anesthesia, brain stimulants, neurolysis.
What does analgesics treat
Analgesic medicine is used in the following cases:
• Field of injury;
• For headache or toothache, after tooth extraction;
• Pain during menstruation;
• Rheumatoid arthritis;
• Fever;
• Migraine;
• Sprain, damage to joints;
• Postoperative pain;
• Prevention of myocardial infarction;
• Heart pain caused by angina pectoris;
• Prevention of a heart attack;
• Prevention of peripheral arterial thromboembolism
Which analgesics have antipyretic properties
During fever, analgesic medicine, which has an antipyretic effect, can be used. We list the analgesics that have these properties:
• NSAIDs: ibuprofen, nimisulide, ketoprofen, naproxen
• Salicylates: aspirin
• Paracetamol
• Nabumeton
• Phenazone (antipyrine)
Why do analgesics contain caffeine
It is known that caffeine can be effective in treating headaches, but there is also such a phenomenon as ricocheting headaches. That is why analgesics for pain with caffeine should be prescribed by your doctor.
Caffeine can increase the effectiveness of analgesics by 40%. Another property of caffeine-containing painkillers combined is the reduction of side effects and addiction syndrome compared to taking high-dose analgesics.
What analgesics contain caffeine:
• Vivarin: 200 mg
• NoDoz Maximum Strength: 200 mg
• Aspirin-Free Excedrin Caplets: 65 mg
• Excedrin Extra Strength Caplets and Tablets: 65 mg.
• Excedrin Migraine: 65 mg.
• Goody’s Cool Orange Powder: 65 mg.
• Pain Reliever Plus Tablets: 65 mg.
• Midol Menstrual Maximum Strength Caplets: 60 mg.
• Vanquish Caplets: 33 mg.
• Goody’s Extra Strength Headache Powder: 32.50 mg.
• Anacin Maximum Strength: 32 mg.
• Anacin Tablets and Caplets: 32 mg.
• Goody’s Extra Strength Tablets: 16.25 mg.
All drugs can be bought without a prescription. In addition to taking analgesic pain medicine with caffeine, you can use drinks that contain caffeine, for example: hot chocolate, green tea, chocolate and coffee liqueurs.
Analgesic medicine is available in the Analgesic section at affordable prices. Medicines shipped from Mexico are a convenient and cost-effective way to get medicine without sacrificing your budget. If you have prescription drugs, please contact our specialists. We will check your recipe and ship the order as soon as possible.